The STAT3 inhibitor GPB730 enhances the sensitivity to enzalutamide in prostate cancer cells
Enzalutamide is a second-generation anti-androgen which has shown increased survival in patients with metastatic prostate cancer. However, some patients do not respond to this therapy or will develop resistance to treatment over time. Signal Transducer and Activator of Transcription 3 (STAT3) is kno...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-10-01
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Series: | Translational Oncology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1936523322001541 |