Impact of Pre-Existing Immunity and Age on Antibody Responses to Live Attenuated Influenza Vaccine

Impact of Pre-Existing Immunity and Age on Antibody Responses to Live Attenuated Influenza Vaccine

Live attenuated influenza vaccines (LAIV) typically induce a poor hemagglutination inhibition (HI) response, which is the standard correlate of protection for inactivated influenza vaccines. The significance of the HI response is complicated because the LAIV vaccine primarily induces the local mucos...

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Bibliographic Details
Main Authors: Lukas Hoen, Sarah Lartey, Fan Zhou, Rishi D. Pathirana, Florian Krammer, Kristin G -I Mohn, Rebecca J. Cox, Karl A. Brokstad
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Series:Vaccines
Subjects:
live attenuated influenza vaccine
immune response
functional antibodies
children
adults
Online Access:https://www.mdpi.com/2076-393X/12/8/864

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https://www.mdpi.com/2076-393X/12/8/864

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