Tigecycline Resistance-Associated Mutations in the MepA Efflux Pump in Staphylococcus aureus

ABSTRACT Tigecycline is an important antibacterial drug for treating infection by clinical multidrug-resistant bacteria, and tigecycline-resistant Staphylococcus aureus (TRSA) has been increasingly reported in recent years. Notably, only rpsJ and mepA are associated with the tigecycline resistance o...

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Bibliographic Details
Main Authors: Honghao Huang, Peng Wan, Xinyue Luo, Yixing Lu, Xiaoshen Li, Wenguang Xiong, Zhenling Zeng
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00634-23