308 Targeting Cdk8 to improve Ischemic Fracture Healing

OBJECTIVES/GOALS: There are178 million bone fractures globally each year, and 46% of fractures that have accompanying vascular damage (ischemia) will not heal without surgical intervention. Using single cell RNAseq we identified Cdk8 as a gene upregulated under ischemic fracture. Our work seeks to i...

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Bibliographic Details
Main Authors: Christina Capobianco, Michelle Song, Jeanna Schmanski, Alexis Donneys, Karen Kessell, Tristan Maerz, Kurt Hankenson
Format: Article
Language:English
Published: Cambridge University Press 2024-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866124002796/type/journal_article