Morphological Phenotyping of Organotropic Brain- and Bone-Seeking Triple Negative Metastatic Breast Tumor Cells

Morphological Phenotyping of Organotropic Brain- and Bone-Seeking Triple Negative Metastatic Breast Tumor Cells

Triple negative breast cancer (TNBC) follows a non-random pattern of metastasis to the bone and brain tissue. Prior work has found that brain-seeking breast tumor cells display altered proteomic profiles, leading to alterations in pathways related to cell signaling, cell cycle, metabolism, and extra...

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Bibliographic Details
Main Authors: Ariana Joy L. DeCastro, Marina A. Pranda, Kelsey M. Gray, John Merlo-Coyne, Nathaniel Girma, Madelyn Hurwitz, Yuji Zhang, Kimberly M. Stroka
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cell migration
cell morphology
tumor cells
cell mechanical characterization
focal adhesions
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.790410/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.790410/full

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