Optimal modeling of anti-breast cancer candidate drugs screening based on multi-model ensemble learning with imbalanced data

The imbalanced data makes the machine learning model seriously biased, which leads to false positive in screening of therapeutic drugs for breast cancer. In order to deal with this problem, a multi-model ensemble framework based on tree-model, linear model and deep-learning model is proposed. Based...

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Bibliographic Details
Main Authors: Juan Zhou, Xiong Li, Yuanting Ma, Zejiu Wu, Ziruo Xie, Yuqi Zhang, Yiming Wei
Format: Article
Language:English
Published: AIMS Press 2023-01-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2023237?viewType=HTML