The Diverse Major Histocompatibility Complex Haplotypes of a Common Commercial Chicken Line and Their Effect on Marek’s Disease Virus Pathogenesis and Tumorigenesis

The Diverse Major Histocompatibility Complex Haplotypes of a Common Commercial Chicken Line and Their Effect on Marek’s Disease Virus Pathogenesis and Tumorigenesis

The major histocompatibility complex (MHC) is crucial for appropriate immune responses against invading pathogens. Chickens possess a single predominantly-expressed class I molecule with strong associations between disease resistance and MHC haplotype. For Marek’s disease virus (MDV) infections of c...

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Bibliographic Details
Main Authors: Luca D. Bertzbach, Clive A. Tregaskes, Rebecca J. Martin, Undine-Sophie Deumer, Lan Huynh, Ahmed M. Kheimar, Andelé M. Conradie, Jakob Trimpert, Jim Kaufman, Benedikt B. Kaufer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
major histocompatibility complex (MHC)
B9
B15
B19
B21
resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.908305/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.908305/full

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