Therapeutic potential of ADAM10 modulation in Alzheimer’s disease: a review of the current evidence

Abstract Alzheimer’s disease (AD), the most common neurodegenerative disease worldwide, is caused by loss of neurons and synapses in central nervous system. Several causes for neuronal death in AD have been introduced, the most important of which are extracellular amyloid β (Aβ) accumulation and agg...

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Bibliographic Details
Main Authors: Mohammad Rafi Khezri, Mehdi Mohebalizadeh, Morteza Ghasemnejad-Berenji
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-023-01072-w