Decreased methylation in the SNAI2 and ADAM23 genes associated with de-differentiation and haematogenous dissemination in breast cancers
Abstract Background In breast cancer (BC), deregulation of DNA methylation leads to aberrant expressions and functions of key regulatory genes. In our study, we investigated the relationship between the methylation profiles of genes associated with cancer invasivity and clinico-pathological paramete...
Main Authors: | Lenka Kalinkova, Iveta Zmetakova, Bozena Smolkova, Gabriel Minarik, Tatiana Sedlackova, Viera Horvathova Kajabova, Zuzana Cierna, Michal Mego, Ivana Fridrichova |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-09-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12885-018-4783-x |
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