The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics

The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics

Mitochondria are intracellular organelles that utilize nutrients to generate energy in the form of ATP by oxidative phosphorylation. Mitochondrial DNA (mtDNA) in humans is a 16,569 base pair double-stranded circular DNA that encodes for 13 vital proteins of the electron transport chain. Our understa...

Full description

Bibliographic Details
Main Authors: Sanjana Saravanan, Caitlin J. Lewis, Bhavna Dixit, Matthew S. O’Connor, Alexandra Stolzing, Amutha Boominathan
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomedicines
Subjects:
mitochondria
mtDNA
mtDNA mutations
mitochondrial diseases
mtDNA editing
allotopic expression
Online Access:https://www.mdpi.com/2227-9059/10/2/490

Internet

https://www.mdpi.com/2227-9059/10/2/490

Similar Items