Are standing osmotic gradients the main driver of cerebrospinal fluid production? A computational analysis
Abstract Background The mechanisms of cerebrospinal fluid (CSF) production by the ventricular choroid plexus (ChP) have not been fully deciphered. One prominent hypothesized mechanism is trans-epithelial water transport mediated by accumulation of solutes at the luminal ChP membrane that produces lo...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-03-01
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Series: | Fluids and Barriers of the CNS |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12987-023-00419-2 |