Disrupting Osr1 expression promoted hepatic steatosis and inflammation induced by high-fat diet in the mouse model

NAFLD, regarded as the hepatic manifestation of metabolic syndrome, is the most common form of liver disease in the United States. The Odd-skipped related 1 (Osr1) gene was previously reported to play a critical role in embryonic development and as a cancer repressor gene, however its role in overnu...

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Bibliographic Details
Main Authors: Ernest C. Lynch, Zhimin Liu, Lin Liu, Xian Wang, Ke K. Zhang, Linglin Xie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9165803/?tool=EBI