Antidiabetic Effect of Rehmanniae Radix Based on Regulation of TRPV1 and SCD1

Antidiabetic Effect of Rehmanniae Radix Based on Regulation of TRPV1 and SCD1

Purpose: This study aimed to disclose the antidiabetic mechanisms of Rehmanniae Radix (RR).Methods: The antidiabetic effect of RR was studied in Streptozocin (STZ)–induced diabetes mellitus (DM) rats and HepG2 cells with insulin resistance (IR). Antidiabetic targets and signaling pathways of RR were...

Full description

Bibliographic Details
Main Authors: Ye Liu, Ruizheng Zhu, Bei Liu, Wuqing Wang, Ping Yang, Zhonglian Cao, Xiaolei Yang, Wandi Du, Qing Yang, Jingru Liang, Jiarong Hu, Guo Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
Rehmanniae Radix
diabetes mellitus
transient receptor potential vanilloid 1
stearoyl-CoA desaturase 1
network pharmacology
transcriptome
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.875014/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.875014/full

Similar Items