Optogenetic frequency scrambling of hippocampal theta oscillations dissociates working memory retrieval from hippocampal spatiotemporal codes

How temporal coordination of neurons in the hippocampus contributes to memory function is not well understood. Here the authors show that abolishing hippocampal theta oscillations lead to impaired working and episodic memory while leaving spatiotemporal codes intact.

Bibliographic Details
Main Authors: Guillaume Etter, Suzanne van der Veldt, Jisoo Choi, Sylvain Williams
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-35825-5