Identification of the Transcriptional Biomarkers Panel Linked to Pathological Remodelling of the Eye Tissues in Various HD Mouse Models

Identification of the Transcriptional Biomarkers Panel Linked to Pathological Remodelling of the Eye Tissues in Various HD Mouse Models

Ocular abnormalities are becoming associated with a spectrum of pathological events in various neurodegenerative diseases. Huntington’s disease (HD) is just such an example of a fatal neurological disorder, where mutated genes (CAG trinucleotide expansions in the <i>Huntingtin</i> gene)...

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Bibliographic Details
Main Authors: Iwona Mazur-Michałek, Marcin Ruciński, Mateusz Sowiński, Paulina Pietras, Marta Leśniczak-Staszak, Witold Szaflarski, Mark Isalan, Michal Mielcarek
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
Huntington’s disease
ocular neurodegeneration
retina
transcriptional deregulation
biomarkers
mouse models
Online Access:https://www.mdpi.com/2073-4409/11/10/1675

Internet

https://www.mdpi.com/2073-4409/11/10/1675

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