Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells

Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells

Abstract Background Reduced supplies of oxygen and nutrients caused by vascular injury lead to difficult-to-heal pressure ulcers (PU) in clinical practice. Rapid vascular repair in the skin wound is the key to the resolution of this challenge, but clinical measures are still limited. We described th...

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Bibliographic Details
Main Authors: Liwen Luo, Hongyu Zhang, Shiyu Zhang, Chengqin Luo, Xuewei Kan, Jun Lv, Ping Zhao, Zhiqiang Tian, Changqing Li
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Nanobiotechnology
Subjects:
Extracellular vesicles
MFGE8
Pressure ulcers
Silk fibroin nanoparticles
Vascular endothelial cells
Online Access:https://doi.org/10.1186/s12951-023-02185-7

Internet

https://doi.org/10.1186/s12951-023-02185-7

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