Molecular docking assessment of pyridone derivatives as glucokinase activators

Molecular docking assessment of pyridone derivatives as glucokinase activators

Background: Mutations in glucokinase (GK) gene results in maturity onset diabetes of the young 2 (MODY2). It has been observed that GK activators (GKAs) can activate GK structure and promote glucose phosphorylation and bring blood glucose levels to normal condition. The present study is aimed to ide...

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Bibliographic Details
Main Authors: Y. Nanda Kumar, J.A. Pradeep Kiran, K. Kalpana, M. Bhaskar, P. Santhosh Kumar, S.Yeswanth, P.V.G.K. Sarma, V. Koteswara Rao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-10-01
Series:Journal of Clinical and Scientific Research
Subjects:
Glucokinase
Maturity onset diabetes of the young 2
Molecular docking
Glucokinase activators
Online Access:http://svimstpt.ap.nic.in/jcsr/oct-dec%2012_files/oa2.pdf

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http://svimstpt.ap.nic.in/jcsr/oct-dec%2012_files/oa2.pdf

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