Interest of Homodialkyl Neamine Derivatives against Resistant <i>P. aeruginosa</i>, <i>E. coli</i>, and β-Lactamases-Producing Bacteria—Effect of Alkyl Chain Length on the Interaction with LPS

Interest of Homodialkyl Neamine Derivatives against Resistant <i>P. aeruginosa</i>, <i>E. coli</i>, and β-Lactamases-Producing Bacteria—Effect of Alkyl Chain Length on the Interaction with LPS

Development of novel therapeutics to treat antibiotic-resistant infections, especially those caused by ESKAPE pathogens, is urgent. One of the most critical pathogens is <i>P. aeruginosa</i>, which is able to develop a large number of factors associated with antibiotic resistance, includ...

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Bibliographic Details
Main Authors: Jitendriya Swain, Clément Dezanet, Hussein Chalhoub, Marie Auquière, Julie Kempf, Jean-Luc Décout, Marie-Paule Mingeot-Leclercq
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
amphiphilic aminoglycosides
antibiotics
<i>P. aeruginosa</i>
ESBL
lipopolysaccharides
bacterial lipid membrane
Online Access:https://www.mdpi.com/1422-0067/22/16/8707

Internet

https://www.mdpi.com/1422-0067/22/16/8707

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