2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione Ameliorates Diabetic Cognitive Impairment Through Inhibiting Hif3α and Apoptosis

2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione Ameliorates Diabetic Cognitive Impairment Through Inhibiting Hif3α and Apoptosis

Diabetes mellitus (DM) is an independent risk factor for cognitive impairment. Although the etiology of diabetic cognitive impairment is complex and multifactorial, the hippocampus neuronal apoptosis is recognized as a main cause of diabetes-induced cognitive impairment. 2-Dodecyl-6-methoxycyclohexa...

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Bibliographic Details
Main Authors: Lihui Wang, Jinjin Cao, Qianqian Xu, Xiaomei Lu, Xin Yang, Qiong Song, Shuai Chen, Kechen Du, Renbin Huang, Chunlin Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pharmacology
Subjects:
DMDD
diabetic cognitive impairment
db/db mice
neuronal apoptosis
Hif3a
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.708141/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.708141/full

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