Fluorophore-Assisted Click Chemistry through Copper(I) Complexation

Fluorophore-Assisted Click Chemistry through Copper(I) Complexation

The copper-catalyzed alkyne-azide cycloaddition (CuAAC) is one of the most powerful chemical strategies for selective fluorescent labeling of biomolecules in in vitro or biological systems. In order to accelerate the ligation process and ensure efficient formation of conjugates under diluted conditi...

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Bibliographic Details
Main Authors: Victor Flon, Magalie Bénard, Damien Schapman, Ludovic Galas, Pierre-Yves Renard, Cyrille Sabot
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biomolecules
Subjects:
click chemistry
CuAAC
chelating fluorophore
chelating azide
fluorescent labeling
azaphthalimide
Online Access:https://www.mdpi.com/2218-273X/10/4/619

Internet

https://www.mdpi.com/2218-273X/10/4/619

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