RNA helicase IGHMBP2 regulates THO complex to ensure cellular mRNA homeostasis

RNA helicase IGHMBP2 regulates THO complex to ensure cellular mRNA homeostasis

Summary: RNA helicases constitute a large protein family implicated in cellular RNA homeostasis and disease development. Here, we show that the RNA helicase IGHMBP2, linked to the neuromuscular disorder spinal muscular atrophy with respiratory distress type 1 (SMARD1), associates with polysomes and...

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Bibliographic Details
Main Authors: Archana Bairavasundaram Prusty, Anja Hirmer, Julieth Andrea Sierra-Delgado, Hannes Huber, Ulf-Peter Guenther, Andreas Schlosser, Olexandr Dybkov, Ezgi Yildirim, Henning Urlaub, Kathrin C. Meyer, Sibylle Jablonka, Florian Erhard, Utz Fischer
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
CP: Molecular biology
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S221112472400130X

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http://www.sciencedirect.com/science/article/pii/S221112472400130X

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