YAP1 plays a key role of the conversion of normal fibroblasts into cancer-associated fibroblasts that contribute to prostate cancer progression

Abstract Background Cancer-associated fibroblasts (CAFs) are an important part of the tumour microenvironment, and their functions are of great concern. This series of experiments aimed to explore how Yes-associated protein 1 (YAP1) regulates the function of stromal cells and how the normal fibrobla...

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Bibliographic Details
Main Authors: Tianyu Shen, Yang Li, Shimiao Zhu, Jianpeng Yu, Boya Zhang, Xuanrong Chen, Zheng Zhang, Yuan Ma, Yuanjie Niu, Zhiqun Shang
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-020-1542-z