The Mandible Ameliorates Facial Allograft Rejection and Is Associated with the Development of Regulatory T Cells and Mixed Chimerism

The Mandible Ameliorates Facial Allograft Rejection and Is Associated with the Development of Regulatory T Cells and Mixed Chimerism

Vascularized composite allografts contain various tissue components and possess relative antigenicity, eliciting different degrees of alloimmune responses. To investigate the strategies for achieving facial allograft tolerance, we established a mouse hemiface transplant model, including the skin, mu...

Full description

Bibliographic Details
Main Authors: Dante De Paz, Ana Elena Aviña, Esteban Cardona, Chin-Ming Lee, Chia-Hsien Lin, Cheng-Hung Lin, Fu-Chan Wei, Aline Yen Ling Wang
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
vascularized composite allotransplantation
facial transplantation
mice
mandible
regulatory T cells
mixed chimerism
Online Access:https://www.mdpi.com/1422-0067/22/20/11104

Internet

https://www.mdpi.com/1422-0067/22/20/11104

Similar Items