Studies of Genetic and Proteomic Risk Factors of Amyotrophic Lateral Sclerosis Inspire Biomarker Development and Gene Therapy

Studies of Genetic and Proteomic Risk Factors of Amyotrophic Lateral Sclerosis Inspire Biomarker Development and Gene Therapy

Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease affecting the upper and lower motor neurons, leading to muscle weakness, motor impairments, disabilities and death. Approximately 5–10% of ALS cases are associated with positive family history (familial ALS or fALS), whils...

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Bibliographic Details
Main Authors: Eva Bagyinszky, John Hulme, Seong Soo A. An
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
amyotrophic lateral sclerosis
biomarkers
genetic factors
proteomic markers
therapy
diagnosis
Online Access:https://www.mdpi.com/2073-4409/12/15/1948

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https://www.mdpi.com/2073-4409/12/15/1948

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