Comprehensive RNAseq analysis reveals PIK3CD promotes glioblastoma tumorigenesis by mediating PI3K-Akt signaling pathway

Comprehensive RNAseq analysis reveals PIK3CD promotes glioblastoma tumorigenesis by mediating PI3K-Akt signaling pathway

Background and Aim: Glioblastoma (GBM) is the most common and aggressive form of primary malignant brain tumors. Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta (PIK3CD), which is overexpressed in GBM, is involved in GBM pathogenesis and drug resistance. However, the molecular...

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Bibliographic Details
Main Authors: Zulfikar Azam, Wei Shao, Ho-keung Ng, Jing Wang, Zhong-ping Chen, Shing-shun Tony To
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Glioma
Subjects:
glioblastoma
integrin
mesenchymal transformation
phosphatidylinositol 3-kinase-akt
phosphatidylinositol-4
5-bisphosphate 3-kinase catalytic subunit delta knock-out
rnaseq
Online Access:http://www.jglioma.com/article.asp?issn=2589-6113;year=2020;volume=3;issue=3;spage=135;epage=142;aulast=

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http://www.jglioma.com/article.asp?issn=2589-6113;year=2020;volume=3;issue=3;spage=135;epage=142;aulast=

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