Involvement of CUL4A in Regulation of Multidrug Resistance to P-gp Substrate Drugs in Breast Cancer Cells

Involvement of CUL4A in Regulation of Multidrug Resistance to P-gp Substrate Drugs in Breast Cancer Cells

CUL4A encodes a core component of a cullin-based E3 ubiquitin ligase complex that regulates many critical processes such as cell cycle progression, DNA replication, DNA repair and chromatin remodeling by targeting a variety of proteins for ubiquitination and degradation. In the research described in...

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Bibliographic Details
Main Authors: Yunshan Wang, Guangxin Ma, Qin Wang, Mingxin Wen, Yangyang Xu, Xiuquan He, Pengju Zhang, Yuli Wang, Taomei Yang, Panpan Zhan, Guangwei Wei
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:Molecules
Subjects:
multidrug resistant
P-glycoprotein
CUL4A
breast cancer
Online Access:http://www.mdpi.com/1420-3049/19/1/159

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http://www.mdpi.com/1420-3049/19/1/159

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