Combined effect of regulatory polymorphisms on transcription of <it>UGT1A1 </it>as a cause of Gilbert syndrome

<p>Abstract</p> <p>Background</p> <p>Gilbert syndrome is caused by defects in bilirubin UDP-glucuronosyltransferase (UGT1A1). The most common variation believed to be involved is A(TA)7TAA. Although several polymorphisms have been found to link with A(TA)7TAA, the combi...

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Bibliographic Details
Main Authors: Sato Hiroshi, Maruo Yoshihiro, Matsui Katsuyuki, Takeuchi Yoshihiro
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/10/57