Genetic architecture of recent-onset dilated cardiomyopathy in Moravian region assessed by whole-exome sequencing and its clinical correlates

Genetic architecture of recent-onset dilated cardiomyopathy in Moravian region assessed by whole-exome sequencing and its clinical correlates

Aims: Recent-onset dilated cardiomyopathy (RODCM) is a disease of heterogeneous aetiology and clinical outcome. In this pilot study, we aimed to assess its genetic architecture and correlate genotype with left ventricular reverse remodelling (LVRR). Patients and Methods: In this multi-centre prospec...

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Bibliographic Details
Main Authors: Anna Chaloupka, Lenka Piherova, Ilga Grochova, Jana Binova, Jan Krejci, Lenka Spinarova, Viktor Stranecky, Stanislav Kmoch, Milos Kubanek
Format: Article
Language:English
Published: Palacký University Olomouc, Faculty of Medicine and Dentistry 2019-12-01
Series:Biomedical Papers
Subjects:
dilated cardiomyopathy
familial cardiomyopathy
next generation sequencing
genetic architecture
cardiac remodelling
Online Access:https://biomed.papers.upol.cz/artkey/bio-201904-0004_genetic-architecture-of-recent-onset-dilated-cardiomyopathy-in-moravian-region-assessed-by-whole-exome-sequenci.php

Internet

https://biomed.papers.upol.cz/artkey/bio-201904-0004_genetic-architecture-of-recent-onset-dilated-cardiomyopathy-in-moravian-region-assessed-by-whole-exome-sequenci.php

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