Establishment of a novel ER-stress induced myopia model in mice

Abstract Background Recent studies have indicated a strong correlation between endoplasmic reticulum (ER) stress and myopia and that eyedrops containing the ER stress inducer tunicamycin (Tm) can induce myopic changes in C57BL/6 J mice. Therefore, this study aimed to create a new myopia model using...

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Bibliographic Details
Main Authors: Longdan Kang, Shin-ichi Ikeda, Yajing Yang, Heonuk Jeong, Junhan Chen, Yan Zhang, Kazuno Negishi, Kazuo Tsubota, Toshihide Kurihara
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Eye and Vision
Subjects:
Online Access:https://doi.org/10.1186/s40662-023-00361-2