Cancer-associated fibroblasts: tumor defenders in radiation therapy

Abstract Cancer-associated fibroblasts (CAFs) are an important component of the tumor microenvironment that are involved in multiple aspects of cancer progression and considered contributors to tumor immune escape. CAFs exhibit a unique radiation resistance phenotype, and can survive clinical radiat...

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Bibliographic Details
Main Authors: Yalin Zhang, Na Lv, Manshi Li, Ming Liu, Chunli Wu
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06060-z