A Bioreactor for 3D In Vitro Modeling of the Mechanical Stimulation of Osteocytes

The bone is a mechanosensitive organ that is also a common metastatic site for prostate cancer. However, the mechanism by which the tumor interacts with the bone microenvironment to further promote disease progression remains to be fully understood. This is largely due to a lack of physiological yet...

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Bibliographic Details
Main Authors: Koh Meng Aw Yong, Eric Horst, Dylan Neale, Sonya Royzenblat, Joerg Lahann, Colin Greineder, Megan Weivoda, Geeta Mehta, Evan T. Keller
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.797542/full