Modulation of the Unfolded Protein Response by the Human Hepatitis B Virus

During productive viral infection the host cell is confronted with synthesis of a vast amount of viral proteins which must be folded, quality controlled, assembled and secreted, perturbing the normal function of the endoplasmic reticulum (ER). To counteract the ER stress, cells activate specific sig...

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Bibliographic Details
Main Authors: Norica eBranza-Nichita, Catalin eLazar, Mihaela eUta
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00433/full