Decoding the transcriptome of calcified atherosclerotic plaque at single-cell resolution
Single-cell RNA sequencing and systems biology are used to profile the human vascular cell populations in calcified atherosclerotic core plaques from carotid endarterectomy samples, showing an anatomic distinction between gene expression of inflammatory versus matrix-secreting factors.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-10-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-022-04056-7 |