Multipotent adult progenitor cells prevent functional impairment and improve development in inflammation driven detriment of preterm ovine lungs

Multipotent adult progenitor cells prevent functional impairment and improve development in inflammation driven detriment of preterm ovine lungs

Background: Perinatal inflammation increases the risk for bronchopulmonary dysplasia in preterm neonates, but the underlying pathophysiological mechanisms remain largely unknown. Given their anti-inflammatory and regenerative capacity, multipotent adult progenitor cells (MAPC) are a promising cell-b...

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Bibliographic Details
Main Authors: Sophie M.L. Neuen, Daan R.M.G. Ophelders, Helene Widowski, Matthias C. Hütten, Tim Brokken, Charlotte van Gorp, Peter G.J. Nikkels, Carmen A.H. Severens-Rijvers, Mireille M.J.P.E. Sthijns, Clemens A. van Blitterswijk, Freddy J. Troost, Vanessa L.S. LaPointe, Shahab Jolani, Christof Seiler, J. Jane Pillow, Tammo Delhaas, Niki L. Reynaert, Tim G.A.M. Wolfs
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Regenerative Therapy
Subjects:
Prenatal inflammation
Postnatal ventilation
Preterm birth
Bronchopulmonary dysplasia
Stem cell therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320424000464

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http://www.sciencedirect.com/science/article/pii/S2352320424000464

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