The SIRT2 Pathway Is Involved in the Antiproliferative Effect of Flavanones in Human Leukemia Monocytic THP-1 Cells

Acute myeloid leukemia (AML) represents the most alarming hematological disease for adults. Several genetic modifications are known to be pivotal in AML; however, SIRT2 over-expression has attracted the scientific community’s attention as an unfavorable prognostic marker. The plant kingdom is a trea...

Full description

Bibliographic Details
Main Authors: Caterina Russo, Alessandro Maugeri, Laura De Luca, Rosaria Gitto, Giovanni Enrico Lombardo, Laura Musumeci, Giovambattista De Sarro, Santa Cirmi, Michele Navarra
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/10/2383