Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation

Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation

BackgroundPancreas transplant alone (PTA) recipients are more affected by pancreas graft thrombosis, and graft loss compared to simultaneous pancreas-kidney (SPK) recipients. The pathophysiology is unknown, but an increased immune response has been suggested in the PTA recipients. In this observatio...

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Bibliographic Details
Main Authors: Kristina Rydenfelt, Gisle Kjøsen, Rune Horneland, Judith Krey Ludviksen, Trond Geir Jenssen, Pål-Dag Line, Tor Inge Tønnessen, Tom Eirik Mollnes, Håkon Haugaa, Søren Erik Pischke
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
thromboinflammation
pancreas transplant alone
simultaneous pancreas-kidney transplantation
pancreas graft thrombosis
complement
cytokines
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1044444/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1044444/full

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