LncRNA TIALD contributes to hepatocellular carcinoma metastasis via inducing AURKA lysosomal degradation

Abstract The N6-methyladenosine (m6A) RNA methyltransferase METTL16 is an emerging player in RNA modification landscape and responsible for the deposition of m6A in a few transcripts. AURKA (aurora kinase A) has been confirmed as an oncogene in cancer development including hepatocellular carcinoma (...

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Main Authors: Yingchao Wang, Yue Zhong, Xiaoyuan Zheng, Niangmei Cheng, Yong Yang, Ye Yang, Fei Wang, Qiuyu Zhuang, Yao Huang, Wuhua Guo, Naishun Liao, Xiaoyu Yang, Bixing Zhao, Xiaolong Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01620-w