Transcriptomic landscape of TIMP3 oncosuppressor activity in thyroid carcinoma

Transcriptomic landscape of TIMP3 oncosuppressor activity in thyroid carcinoma

Abstract Background Papillary thyroid cancer (PTC) is the most frequent thyroid tumor. The tissue inhibitor of metalloproteinase-3 (TIMP3) gene encodes a matrix metalloproteinases inhibitor that exerts a tumor suppressor role in several tumor types. TIMP3 is frequently downregulated in PTC by promot...

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Bibliographic Details
Main Authors: M. Mazzoni, K. Todoerti, L. Agnelli, E. Minna, S. Pagliardini, T. Di Marco, M. G. Borrello, A. Neri, A. Greco
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cancer Cell International
Subjects:
TIMP3
Thyroid carcinoma
Inflammation
Gene expression
Online Access:https://doi.org/10.1186/s12935-022-02811-8

Internet

https://doi.org/10.1186/s12935-022-02811-8

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