Sertaconazole-repurposed nanoplatform enhances lung cancer therapy via CD44-targeted drug delivery

Sertaconazole-repurposed nanoplatform enhances lung cancer therapy via CD44-targeted drug delivery

Abstract Background Lung cancer is one of the most frequent causes of cancer-related deaths worldwide. Drug repurposing and nano-drug delivery systems are attracting considerable attention for improving anti-cancer therapy. Sertaconazole (STZ), an antifungal agent, has been reported to exhibit cytot...

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Bibliographic Details
Main Authors: Ruolan Liu, Qiong Li, Siyuan Qin, Ling Qiao, Mei Yang, Shanshan Liu, Edouard C. Nice, Wei Zhang, Canhua Huang, Shaojiang Zheng, Wei Gao
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Sertaconazole
Drug repurposing
Lung cancer
Nanoparticle
Targeted delivery
Online Access:https://doi.org/10.1186/s13046-023-02766-2

Internet

https://doi.org/10.1186/s13046-023-02766-2

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