The Role of Targeted Osmotic Lysis in the Treatment of Advanced Carcinoma in Companion Animals: A Case Series

Background. Targeted osmotic lysis (TOL) is a novel technology that involves concomitant stimulation of voltage-gated sodium channels (VGSCs) and the pharmacological blockade of Na+, K+-ATPase causing lysis of highly malignant cancer cells. Hypothesis/Objectives. TOL offers an option for treating ad...

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Bibliographic Details
Main Authors: Harry J. Gould, Samantha Edenfield, Paige R. Miller, Kelly Jean Sherman, Brian Melius, Alissa Whitney, Robert P. Hunter, Fabio Del Piero, Dennis Tracey, Dennis Paul
Format: Article
Language:English
Published: Hindawi Limited 2022-01-01
Series:Case Reports in Veterinary Medicine
Online Access:http://dx.doi.org/10.1155/2022/2747108