Assesment of Postoperative Analgesic Effects of Intramuscular Tramadol Administration and Intraperitoneal Bupivacaine following Laparoscopic Cholecystectomy
Background: For postoperative pain relief after laparoscopic surgeries, intramuscular or intravenous non-steroidal anti-inflammatory drugs and opioids, infiltration at the incision site with local anesthetics, intraperitoneal infiltration of local anesthetics with adjuvants, epidurals and nerve blo...
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| Format: | Article |
| Language: | English |
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Interdisciplinary Academy of Pain Medicine
2023-10-01
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| Series: | Медицина болю |
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| Online Access: | https://painmedicine.org.ua/index.php/pnmdcn/article/view/347 |
| _version_ | 1797666350593736704 |
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| author | Deepthi Griddaluru S Brinda Kuraparthy Dwarakanath Reddy Vembuluru Swapna Vankadara Krishna Chaitanya Kandukuru |
| author_facet | Deepthi Griddaluru S Brinda Kuraparthy Dwarakanath Reddy Vembuluru Swapna Vankadara Krishna Chaitanya Kandukuru |
| author_sort | Deepthi Griddaluru S |
| collection | DOAJ |
| description |
Background: For postoperative pain relief after laparoscopic surgeries, intramuscular or intravenous non-steroidal anti-inflammatory drugs and opioids, infiltration at the incision site with local anesthetics, intraperitoneal infiltration of local anesthetics with adjuvants, epidurals and nerve blocks were in use. The study was aimed to assess the efficacy of intramuscular Tramadol and intraperitoneal instillation of bupivacaine on postoperative analgesia, postoperative nausea, and vomiting following laparoscopic cholecystectomy.
Methods: This study included 60 American Society of Anesthesiologists (ASA) I and ASA II patients of aged 18-60 years who were scheduled for laparoscopic cholecystectomy under general anesthesia. 60 patients were classified randomly into two groups equally: Group T received 100 Mg of intramuscular tramadol and Group B received intraperitoneal instillation of 30 ml of plain bupivacaine. Time duration, postoperative pain, haemodynamics, nausea, vomiting, and time taken to rescue analgesia were noted.
Results: The time for onset of analgesia was 6.51 ± 2.41min in group T and 7.61 ± 2.19 min in group B (p=0.039). The duration of analgesia was 2.37 ± 0.67 hours in group T and 3.65 ± 0.79 hours in group B (p=0.002). VAS Score was significantly lower in Group T than Group B at 1hr, 2hr, 4hr and 6hr (p <0.05). Intraperitoneal bupivacaine showed a significant reduction in postoperative pain for the first 6 hours postoperatively (P<0.05), and time taken to rescue analgesia requirement was prolonged (P<0.05). The rescue analgesia consumption of Paracetamol was 1.5 grams in group-B and 2.5 grams in group T (P<0.05) in 24 hr post-surgery. Nausea and vomiting were observed in 2 cases, and shoulder pain in one case in group T.
Conclusion: Bupivacaine is effective in reducing postoperative pain, and it prolongs the requirement time for rescue analgesia after LC surgery. It also required less consumption of rescue analgesic without fluctuations in hemodynamics
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| first_indexed | 2024-03-11T19:57:17Z |
| format | Article |
| id | doaj.art-40e527a3bcbb47db91fc401d355243bd |
| institution | Directory Open Access Journal |
| issn | 2414-3812 2519-2752 |
| language | English |
| last_indexed | 2024-03-11T19:57:17Z |
| publishDate | 2023-10-01 |
| publisher | Interdisciplinary Academy of Pain Medicine |
| record_format | Article |
| series | Медицина болю |
| spelling | doaj.art-40e527a3bcbb47db91fc401d355243bd2023-10-04T15:23:34ZengInterdisciplinary Academy of Pain MedicineМедицина болю2414-38122519-27522023-10-0181-210.31636/pmjua.v8i1-2.4Assesment of Postoperative Analgesic Effects of Intramuscular Tramadol Administration and Intraperitoneal Bupivacaine following Laparoscopic CholecystectomyDeepthi Griddaluru S 0Brinda Kuraparthy1Dwarakanath Reddy Vembuluru2Swapna Vankadara 3Krishna Chaitanya Kandukuru4Assistant Professor, Department of Anaesthesia, Narayana Medical College & Hospital, Nellore, A.P. India.Assistant Professor, Department of Anaesthesia, Narayana Medical College & Hospital, Nellore, A.P. India.Associate Professor, Department of Surgical Gastroenterology, Narayana Medical College & Hospital, Nellore, A.P. IndiaAssistant Professor, Department of Anaesthesia, Narayana Medical College & Hospital, Nellore, A.P. India.Professor, Department of Anaesthesia, Narayana Medical College & Hospital, Nellore, A.P. India. Background: For postoperative pain relief after laparoscopic surgeries, intramuscular or intravenous non-steroidal anti-inflammatory drugs and opioids, infiltration at the incision site with local anesthetics, intraperitoneal infiltration of local anesthetics with adjuvants, epidurals and nerve blocks were in use. The study was aimed to assess the efficacy of intramuscular Tramadol and intraperitoneal instillation of bupivacaine on postoperative analgesia, postoperative nausea, and vomiting following laparoscopic cholecystectomy. Methods: This study included 60 American Society of Anesthesiologists (ASA) I and ASA II patients of aged 18-60 years who were scheduled for laparoscopic cholecystectomy under general anesthesia. 60 patients were classified randomly into two groups equally: Group T received 100 Mg of intramuscular tramadol and Group B received intraperitoneal instillation of 30 ml of plain bupivacaine. Time duration, postoperative pain, haemodynamics, nausea, vomiting, and time taken to rescue analgesia were noted. Results: The time for onset of analgesia was 6.51 ± 2.41min in group T and 7.61 ± 2.19 min in group B (p=0.039). The duration of analgesia was 2.37 ± 0.67 hours in group T and 3.65 ± 0.79 hours in group B (p=0.002). VAS Score was significantly lower in Group T than Group B at 1hr, 2hr, 4hr and 6hr (p <0.05). Intraperitoneal bupivacaine showed a significant reduction in postoperative pain for the first 6 hours postoperatively (P<0.05), and time taken to rescue analgesia requirement was prolonged (P<0.05). The rescue analgesia consumption of Paracetamol was 1.5 grams in group-B and 2.5 grams in group T (P<0.05) in 24 hr post-surgery. Nausea and vomiting were observed in 2 cases, and shoulder pain in one case in group T. Conclusion: Bupivacaine is effective in reducing postoperative pain, and it prolongs the requirement time for rescue analgesia after LC surgery. It also required less consumption of rescue analgesic without fluctuations in hemodynamics https://painmedicine.org.ua/index.php/pnmdcn/article/view/347bupivacainecholecystectomyhemodynamicstramadolwound infection |
| spellingShingle | Deepthi Griddaluru S Brinda Kuraparthy Dwarakanath Reddy Vembuluru Swapna Vankadara Krishna Chaitanya Kandukuru Assesment of Postoperative Analgesic Effects of Intramuscular Tramadol Administration and Intraperitoneal Bupivacaine following Laparoscopic Cholecystectomy Медицина болю bupivacaine cholecystectomy hemodynamics tramadol wound infection |
| title | Assesment of Postoperative Analgesic Effects of Intramuscular Tramadol Administration and Intraperitoneal Bupivacaine following Laparoscopic Cholecystectomy |
| title_full | Assesment of Postoperative Analgesic Effects of Intramuscular Tramadol Administration and Intraperitoneal Bupivacaine following Laparoscopic Cholecystectomy |
| title_fullStr | Assesment of Postoperative Analgesic Effects of Intramuscular Tramadol Administration and Intraperitoneal Bupivacaine following Laparoscopic Cholecystectomy |
| title_full_unstemmed | Assesment of Postoperative Analgesic Effects of Intramuscular Tramadol Administration and Intraperitoneal Bupivacaine following Laparoscopic Cholecystectomy |
| title_short | Assesment of Postoperative Analgesic Effects of Intramuscular Tramadol Administration and Intraperitoneal Bupivacaine following Laparoscopic Cholecystectomy |
| title_sort | assesment of postoperative analgesic effects of intramuscular tramadol administration and intraperitoneal bupivacaine following laparoscopic cholecystectomy |
| topic | bupivacaine cholecystectomy hemodynamics tramadol wound infection |
| url | https://painmedicine.org.ua/index.php/pnmdcn/article/view/347 |
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