Novel acetylcholinesterase inhibitors: Synthesis, docking and inhibitory activity evaluation of 4-benzamido-N-(1-benzylpiperidin-4-yl) benzamide derivatives

The cholinergic hypothesis is one of the basic approaches for designing and discovering novel anti-Alzheimer drugs. Application of the pharmacophore of well-known drugs like donepezil helps us achieve new molecules. In the current project, a new series of benzamide derivatives (6a–6l) were designed...

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Bibliographic Details
Main Authors: Ahmad Mohammadi-Farani, Sara Nazari, Mahsa Mohammadi, Sahar Jamshidy Navid, Amin Hosseini, Alireza Aliabadi
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221171562300512X