Extracellular vesicle microRNA and protein cargo profiling in three clinical-grade stem cell products reveals key functional pathways

Extracellular vesicle microRNA and protein cargo profiling in three clinical-grade stem cell products reveals key functional pathways

The cell origin-specific payloads within extracellular vesicles (EVs) mediate therapeutic bioactivity for a wide variety of stem cell types. In this study, we profiled the microRNA (miRNA) and protein cargos found within EVs produced by three clinical-grade stem cell products of different ontogenies...

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Bibliographic Details
Main Authors: Ramana Vaka, Sandrine Parent, Yousef Risha, Saad Khan, David Courtman, Duncan J. Stewart, Darryl R. Davis
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Special Issue - Exploiting Extracellular Vesicles as Therapeutic Agents
stem cells
extracellular vesicles
microRNA
proteins
functional enrichment
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123000549

Internet

http://www.sciencedirect.com/science/article/pii/S2162253123000549

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