Blockage of αvβ3 integrin in 3D culture of triple-negative breast cancer and endothelial cells inhibits migration and discourages endothelial-to-mesenchymal plasticity

Blockage of αvβ3 integrin in 3D culture of triple-negative breast cancer and endothelial cells inhibits migration and discourages endothelial-to-mesenchymal plasticity

Breast cancer is a relevant cause of mortality in women and its triple-negative subtype (TNBC) is usually associated with poor prognosis. During tumor progression to metastasis, angiogenesis is triggered by the sprouting of endothelial cells from pre-existing vessels by a dynamic chain of events inc...

Full description

Bibliographic Details
Main Authors: Bruna Carla Casali, Matheus Pintor Baptista, Bianca Cruz Pachane, Anelise Abreu Cortez, Wanessa Fernanda Altei, Heloísa Sobreiro Selistre-de-Araújo
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Biochemistry and Biophysics Reports
Subjects:
3D culture
αvβ3 integrin
Cell migration
Triple-negative breast cancer
Endothelial cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580824000505

Internet

http://www.sciencedirect.com/science/article/pii/S2405580824000505

Similar Items