Intrathecal dexmedetomidine as an adjuvant to plain ropivacaine for spinal anesthesia during cesarean section: a prospective, double-blinded, randomized trial for ED50 determination using an up-down sequential allocation method

Abstract Background Intrathecal dexmedetomidine, as an adjuvant to local anesthetics, has been reported to improve the quality of spinal anesthesia and reduce the required local anesthetic dose. However, the optimal dosage regimen for intrathecal dexmedetomidine combined with plain ropivacaine for c...

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Bibliographic Details
Main Authors: Xiaofei Mo, Fa Huang, Xiaoying Wu, Jumian Feng, Jiequn Zeng, Jinghui Chen
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Anesthesiology
Subjects:
Online Access:https://doi.org/10.1186/s12871-023-02275-x