Neuroprotective Effect of Subdural Infusion of Serp-1 in Spinal Cord Trauma

Neuroprotective Effect of Subdural Infusion of Serp-1 in Spinal Cord Trauma

Spinal cord injury (SCI) initiates a severe, destructive inflammation with pro-inflammatory, CD68+/CD163−, phagocytic macrophages infiltrating the area of necrosis and hemorrhage by day 3 and persisting for the next 16 weeks. Inhibition of macrophage infiltration of the site of necrosis that is conv...

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Bibliographic Details
Main Authors: Jacek M. Kwiecien, Wojciech Dabrowski, Bryce J. Kwiecien-Delaney, Christian J. Kwiecien-Delaney, Dorota Siwicka-Gieroba, Jordan R. Yaron, Liqiang Zhang, Kathleen H. Delaney, Alexandra R. Lucas
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomedicines
Subjects:
spinal cord injury
macrophage
neuroprotective therapy
Serp-1
cavity of injury
histology
Online Access:https://www.mdpi.com/2227-9059/8/10/372

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https://www.mdpi.com/2227-9059/8/10/372

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