Marrow Mesenchymal Stem Cell-Derived Exosomes Upregulate Astrocytic Glutamate Transporter-1 Expression via miR-124/mTOR Pathway against Oxygen-Glucose Deprivation/Reperfusion Injury

Marrow Mesenchymal Stem Cell-Derived Exosomes Upregulate Astrocytic Glutamate Transporter-1 Expression via miR-124/mTOR Pathway against Oxygen-Glucose Deprivation/Reperfusion Injury

Background: Experimental investigations have reported the efficacy of marrow mesenchymal stem cell-derived exosomes (MSC-Exos) for the treatment of ischemic stroke. The therapeutic mechanism, however, is still unknown. The purpose of the study is to show whether MSC-Exos increases astrocytic glutama...

Full description

Bibliographic Details
Main Authors: Weiyi Huang, Yuansheng Fan, Chen Jiang, Jiantong Jiao, Wei Ji, Hui Huang, Junfei Shao
Format: Article
Language:English
Published: IMR Press 2023-10-01
Series:Journal of Integrative Neuroscience
Subjects:
ischemic stroke
marrow mesenchymal stem cells
exosome
oxygen-glucose deprivation/reperfusion
glt-1
Online Access:https://www.imrpress.com/journal/JIN/22/6/10.31083/j.jin2206144

Internet

https://www.imrpress.com/journal/JIN/22/6/10.31083/j.jin2206144

Similar Items