Near-Infrared Transflectance Spectroscopy Discriminates Solutions Containing Two Commercial Formulations of Botulinum Toxin Type A Diluted at Recommended Volumes for Clinical Reconstitution

Near-Infrared Transflectance Spectroscopy Discriminates Solutions Containing Two Commercial Formulations of Botulinum Toxin Type A Diluted at Recommended Volumes for Clinical Reconstitution

Botulinum neurotoxin type A (BoNT-A) is the active substance in pharmaceutical preparations widely used worldwide for the highly effective treatment of various disorders. Among the three commercial formulations of BoNT-A currently available in Italy for neurological indications, abobotulinum A toxin...

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Bibliographic Details
Main Authors: Antonio Currà, Riccardo Gasbarrone, Giuseppe Bonifazi, Silvia Serranti, Francesco Fattapposta, Carlo Trompetto, Lucio Marinelli, Paolo Missori, Eugenio Lendaro
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Biosensors
Subjects:
NIR spectroscopy
transflectance spectroscopy
botulinum neurotoxin type A
chemometrics
partial least squares-discriminant analysis
Online Access:https://www.mdpi.com/2079-6374/12/4/216

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https://www.mdpi.com/2079-6374/12/4/216

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