LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling

LRP1 loss in airway epithelium exacerbates smoke-induced oxidative damage and airway remodeling

The LDL receptor-related protein 1 (LRP1) partakes in metabolic and signaling events regulated in a tissue-specific manner. The function of LRP1 in airways has not been studied. We aimed to study the function of LRP1 in smoke-induced disease. We found that bronchial epithelium of patients with chron...

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Bibliographic Details
Main Authors: Itsaso Garcia-Arcos, Sangmi S. Park, Michelle Mai, Roger Alvarez-Buve, Lillian Chow, Huchong Cai, Nathalie Baumlin-Schmid, Christina W. Agudelo, Jennifer Martinez, Michael D. Kim, Abdoulaye J. Dabo, Matthias Salathe, Ira J. Goldberg, Robert F. Foronjy
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Journal of Lipid Research
Subjects:
lipoprotein receptors
cell biology
ApoE
receptors
inflammation
animal models
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227522000189

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http://www.sciencedirect.com/science/article/pii/S0022227522000189

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