Efficacy and Safety of the Collagenase of the Bacterium Clostridium Histolyticum for the Treatment of Capsular Contracture after Silicone Implants: Ex-Vivo Study on Human Tissue.

The fibrotic capsule that surrounds silicone implants consists mainly of collagen. The FDA-approved collagenase of the bacterium clostridium histolyticum provides a reasonable treatment option. Safety and efficacy at the female breast site must be evaluated before clinical utilization.We incubated 2...

Full description

Bibliographic Details
Main Authors: Sebastian Fischer, Christoph Hirche, Yannick Diehm, Kristo Nuutila, Jurij Kiefer, Emre Gazyakan, Ericka M Bueno, Thomas Kremer, Ulrich Kneser, Bohdan Pomahac
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4883774?pdf=render